Confidence,
when it counts.

ED Treatment: Sildenafil & TadalafilWomen’s Sexual Health: Bremelanotide Nasal Spray

Three pathways — blood flow, the brain, and desire itself — your provider matches the right one to you.

Find my match
Beyond the standard pill

Nothing to swallow.Nothing to time.

chewable gum one a day TADALAFIL works on blood flow VARDENAFIL a second, same pathway VITAMIN D3 + K2 in the same daily gum the only daily gum on our menu
Epiq Chew
Life on the DESIRE Protocol Olympus, beyond blood flowWHEN THE PILLS HAVEN’T WORKED

Confidence, On Demand.

Prescription only Free shipping Provider review in 24h US-licensed pharmacy
Epiq Chew ships monthly with 3, 6, and 12-month plans — as-needed formats refill only when you use them · Cancel anytime
Compounded medications are not FDA-approved. Product imagery is illustrative only — the bottles, capsules and tablets shown are renderings, not the exact container you will receive. Medications are compounded and dispensed by a licensed U.S. partner pharmacy, and actual packaging, labeling and dosage form appearance will differ.

Always ready

A daily option — never caught off guard.
RXMen

Tadalafil ODT

Tadalafil Under the tongue · on demand The gentle classic — a long window, taken before the moment. $69/moplans from $55
Tadalafil ODTTadalafil Get started Important Safety Information
RXMen

Epiq Chew

Tadalafil + Vardenafil Chewable gum · daily One gum a day — always ready, no planning. $89/moplans from $71
Epiq Chew — Tadalafil + Vardenafil chewableTadalafil + Vardenafil Get started Important Safety Information: tadalafil · vardenafil

For the night you’ve planned

Taken shortly before — ready when you are.
RXMOST VERSATILEMen

Sildenafil + Tadalafil Combo ODT

Under the tongue · on demand Two actives, one troche — covers onset and staying power. $79/moplans from $70
Sildenafil + Tadalafil Combo ODTSildenafil + Tadalafil Get started Important Safety Information: sildenafil · tadalafil
RXMen & women

Olympus

Sublingual tablet · 1 tablet before activity For when pills haven’t worked — adds oxytocin’s pathway. $119/moplans from $95
Olympus — Bremelanotide + Oxytocin sublingual tabletBremelanotide + Oxytocin Get started Important Safety Information: bremelanotide · oxytocin
RXTHE UPGRADEMen

Olympus Peak

Sublingual tablet · 1 tablet before activity Everything Olympus does, plus tadalafil’s window. $129/moplans from $103
Olympus Peak — Bremelanotide + Oxytocin + Tadalafil sublingual tabletBremelanotide + Oxytocin + Tadalafil Get started Important Safety Information: bremelanotide · oxytocin · tadalafil
RXMen

Sildenafil ODT

Under the tongue · on demand The most-prescribed original, dissolving fast. $59/moplans from $56
Sildenafil ODTSildenafil Get started Important Safety Information
RXMen

VAST

Sublingual · 20–30 min before For the ~30% of men single-agent pills don’t work for. $129/moplans from $103
VAST — Apomorphine + Tadalafil + Vardenafil sublingualApomorphine + Tadalafil + Vardenafil Get started Important Safety Information: apomorphine · tadalafil · vardenafil
RXWomen

Bremelanotide Nasal Spray

Nasal spray · about 45 min prior For desire itself — not just blood flow. $155/mo3-month plan · from $152
Bremelanotide Nasal SprayBremelanotide Get started Important Safety Information
Beyond the blue pill

The options most
telehealth brands don’t carry.

Sildenafil and tadalafil are the same everywhere you look. These three work through different pathways — built for men the standard pills didn’t work for.

¹ Reported nonresponse rates to single-agent PDE5 inhibitors in published literature. Prescription only, if appropriate — a licensed provider determines whether any of these is right for you. Compounded medications are not FDA-approved. Important Safety Information

Women’s sexual health

Desire has two sides.

Most sexual-health menus are built for men. The DESIRE Protocol also carries a nasal spray prescribed for women — bremelanotide, compounded by a US-licensed pharmacy and taken about 45 minutes before.

  • What it isBremelanotide, compounded as a nasal spray. For desire itself — not just blood flow.
  • How it’s takenOne spray, about 45 minutes prior. 3, 6, or 12-month plans.
  • Who decidesA licensed provider reviews your intake and determines whether it is appropriate for you.
The DESIRE Protocol bremelanotide nasal spray
Get started $155/mo3-month plan · from $152

Prescription only, if appropriate — a licensed provider determines whether this is right for you. Nuvari’s bremelanotide is compounded by a US-licensed 503A pharmacy; compounded medications are not FDA-approved, and this is not the FDA-approved bremelanotide product. Individual results vary. Important Safety Information

Your confidence, years from now.

Start the DESIRE
Viagra® didn’t work? VAST is built for the ~30% of men it fails¹ Try VAST →

¹ Findings from clinical trials and FDA labeling of approved PDE5 inhibitors in specific populations, and from clinical guidelines on dosing strategies. Nuvari prescribes compounded formulations built on the same classes of active ingredients. Compounded medications are not FDA-approved. Individual results vary. The ~30% figure reflects reported nonresponse rates to single-agent PDE5 inhibitors in published literature. Viagra® and Cialis® are registered trademarks of their respective owners. Nuvari is not affiliated with or endorsed by them.

Compare Your Options
Board-certified physicianslicensed in your state
Compounded by a US pharmacylicensed, audited, traceable
Free, discreet shippingincluded in your subscription
What You’ll Take

On-demand or daily.

Combo troche for on-demand use, or daily low-dose tadalafil. Your provider matches the format to your lifestyle.

Why This Protocol

Two compounds, one goal — your confidence.

Sildenafil for the moment, tadalafil for the lifestyle. Your provider helps you choose.

About this protocol

Mechanism and clinical context our providers reference when evaluating intake.

The medications

  • Sildenafil + Tadalafil Combo ODTfast onset plus a long window
  • Olympus & Olympus Peaksublingual tablets that work beyond blood flow
  • Tadalafil ODT / Sildenafil ODTthe long-established singles
  • Epiq Chew, VAST & Bremelanotidedaily gum, dual-agent tablet, and the nasal spray

Inside the formulas

  • Sildenafil / Tadalafil / VardenafilPDE5 inhibitors — the blood-flow pathway
  • Apomorphineworks through the brain, not just blood flow
  • Bremelanotide & Oxytocinthe desire pathway
  • Vitamin D3 / K2daily co-formulated support

Everything ships at room temperature in unmarked packaging. As-needed formats refill only when you use them. Physician-prescribed and dispensed by a licensed US pharmacy.

Your Performance Arc

First use

Effects begin within 15-30 minutes for the troche, or continuously with daily tadalafil.

Week 1-2

Confidence builds as you find the right timing and dosing.

Month 1

Dialing it in. Your provider can adjust the dose or format if it's not right yet. Individual results vary.

Ongoing

Use as needed or daily — your protocol adapts to your life.

Your timeline to treatment

From personalized intake to ongoing support, we help you get — and stay — on track.

Start The DESIRE Protocol in 5 simple steps

Answer a few questions about your health, goals, and history — all online, no in-person appointment needed.

Take your online intake on your phone

A US-licensed clinician reviews your intake, follows up on anything that needs clarification, and signs your prescription.

A licensed clinician reviews your intake

Your Rx is compounded in a US-licensed 503A pharmacy, lab-tested, sealed, and shipped — never sitting on a shelf.

US-licensed 503A pharmacy compounds your Rx

Your shipment lands at your door with everything you need to start — troches or capsules, step-by-step guidance, and direct access to your provider.

Your shipment arrives at your door

Ongoing care from our medical team — message your provider any time, with quick reviews and dose adjustments when needed.

Ongoing care from your provider

Peer-reviewed research and regulatory documents our medical team consults when evaluating intake for this protocol.

U.S. Food and Drug Administration (DailyMed / NLM)

Viagra (sildenafil citrate) — Full Prescribing Information

Official FDA prescribing information for sildenafil citrate, a PDE5 inhibitor indicated for erectile dysfunction. Provides pharmacology, dosing, contraindications, and drug interaction data referenced by our clinical team.
DailyMed / NLM

View source

U.S. Food and Drug Administration (DailyMed / NLM)

Cialis® (tadalafil) — Full Prescribing Information

Official FDA prescribing information for tadalafil, a PDE5 inhibitor indicated for erectile dysfunction and BPH. Covers on-demand and daily dosing, pharmacokinetics, contraindications, and interaction profiles.
DailyMed / NLM

View source

European Urology (Elsevier)

Phosphodiesterase 5 inhibitors for the treatment of erectile dysfunction: a trade-off network meta-analysis

Systematic review and network meta-analysis comparing the clinical efficacy and safety profiles of approved PDE5 inhibitors for erectile dysfunction, informing the selection of sildenafil and tadalafil in the DESIRE Protocol.
Chen L, Staubli SEL, Schneider MP, et al. — European Urology 2015;68(4):674-680

View source

European Urology (Elsevier)

EAU Guidelines on Male Sexual Dysfunction

European Association of Urology evidence-based clinical guidelines on male sexual dysfunction, covering PDE5 inhibitor therapy, on-demand vs. daily dosing strategies, and contraindication management.
Hatzimouratidis K et al. — European Urology 2010

View source
Medical notice. The DESIRE Protocol is a physician-prescribed medication dispensed only after clinical evaluation. PDE5 inhibitors are contraindicated with nitrate medications and may cause headache, flushing, nasal congestion, or visual disturbances. Not appropriate for patients with unstable cardiovascular disease, recent stroke, or severe hepatic impairment. Discuss all medications with your provider. Statements on this site have not been evaluated by the FDA.
Pairs With

What Desire stacks with.

The protocols our providers most often add alongside this one.

Begin the DESIRE →